Combination of Melatonin and Metformin Hydrochloride for Treatment Polycystic Ovarian in Female Rats
نویسندگان
چکیده
منابع مشابه
Metformin and troglitazone in the treatment of female infertility associated with polycystic ovarian syndrome.
Polycystic ovarian syndrome is the most common cause of anovulatory infertility and causes menstrual disruption in 5-10% females, and is characterized by insulin resistance, hyperinsulinemia, hyperandrogenism and anovulation. Such factors are responsible for the increased miscarriage and infertility in women with PCOS. Administration of various insulin sensitizing drugs, such as metformin and t...
متن کاملcomparison of zoe and vitapex for canal treatment of necrotic primary teeth
چکیده ندارد.
15 صفحه اولEffects of melatonin on the ovarian response to pinealectomy or continuous light in female rats: similarity with polycystic ovary syndrome.
The current study was conducted to investigate the relationship between melatonin and chronic anovulation. Adult (3-4 months old) female Wistar rats were submitted to pinealectomy: group I: pinealectomized ovariectomized melatonin-treated (N = 10); group II: pinealectomized ovariectomized placebo-treated (N = 12); group III: pinealectomized light-treated placebo-treated (N = 10) or maintained u...
متن کاملMetformin Therapy Decreases Hyperandrogenism and Ovarian Volume in Women with Polycystic Ovary Syndrome
Background: It is well known that there is a close relationship between elevated androgen plasma levels and the ultrasound findings of stromal hypertrophy in polycystic ovary syndrome (PCOS). The objective of this study was to investigate the effects metformin on the hyperandrogenism and ovarian volume in PCOS. Methods: The study is an unrandomized clinical trial with before–after desig...
متن کاملMetformin and pioglitazone in polycystic ovarian syndrome: a comparative study.
OBJECTIVES To evaluate the effect of metformin and pioglitazone on insulin resistance, ovulation and hyperandrogenism in women with PCOS. METHODS 100 patients of age 18-30 years were included in this randomised double blind trial for treatment with either metformin or pioglitazone for a period of 6 months. RESULTS Administration of metformin and pioglitazone for 6 months revealed that 50 % ...
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ژورنال
عنوان ژورنال: Acta Scientiae Veterinariae
سال: 2018
ISSN: 1679-9216
DOI: 10.22456/1679-9216.81208